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Treatment of Parkinson's disease and syndrome. It is useful in relieving many of the symptoms of parkinsonism, particularly rigidity and bradykinesia. Sinemet frequently is helpful in the management of tremor, dysphagia, sialorrhea and postural instability associated with Parkinson's disease and syndrome.
When therapeutic response to levodopa alone is irregular, and signs and symptoms of Parkinson's disease are not evenly controlled throughout the day, substitution of Sinemet usually is effective in reducing fluctuations in response.
By reducing certain adverse reactions produced by levodopa alone, Sinemet permits more patients to obtain adequate relief of the symptoms of Parkinson's disease.
Sinemet is also indicated for patients with Parkinsonism who are taking vitamin preparations that contain pyridoxine HCl (vitamin B6).
